Our Mission and Vision

Our mission is to translate complex, powerful biology with rigor and urgency into life-changing medicines.

Our vision is to make lasting scientific contributions that improve human life.

Our Pipeline

We are advancing our broad and diverse pipeline of biologic drug candidates, all discovered in-house, with the goal of addressing significant unmet medical needs in diseases that impact the lives of millions around the world. We are exploring partnering opportunities across our full product candidate and research portfolio.
 

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Aldafermin
Aldafermin

FGF19 Analog

Primary Sclerosing Cholangitis

Phase 2 Trial (Completed); Planning for Potential Registrational Trial

Primary Sclerosing Cholangitis

Phase 2 Trial (Completed); Planning for Potential Registrational Trial

NGM120
NGM120

GFRAL Antagonist Antibody

Hyperemesis Gravidarum

Planning for Phase 2 Trial

Hyperemesis Gravidarum

Planning for Phase 2 Trial

NGM707 + pembrolizumab
NGM707 + pembrolizumab

ILT2/ILT4 Dual Antagonist + PD-1 Antagonist Antibody

Advanced Solid Tumors

Phase 1/2 Trial

Advanced Solid Tumors

Phase 1/2 Trial

NGM831 + NGM438 + pembrolizumab
NGM831 + NGM438 + pembrolizumab

ILT3 + LAIR1 + PD-1 Antagonist Antibodies

Advanced Solid Tumors

Phase 1 (Part 1C) Trial

Advanced Solid Tumors

Phase 1 (Part 1C) Trial

ngm's discovery engine

Biology-Led Innovation

NGM is built on a straightforward central premise: create an environment that allows drug discovery research to thrive by focusing on powerful human biology unconstrained by therapeutic area or technology approach. Regardless of where it leads us, our scientific exploration is grounded in a singular motivation: deliver important medicines to address critical unmet medical needs in grievous diseases. The heart and soul of NGM, our discovery engine fuels ongoing innovation and is the source of our diverse and growing pipeline of candidates.

Meet Our Team

We have an experienced and talented team of in-house scientists and drug developers using their capabilities in discovery sciences, protein and antibody engineering, pharmacology, translational medicine and preclinical and clinical development to discover and develop innovative therapeutics.

Go To Team

Built from scratch. Led by biology. Motivated by patients.

Our Discovery Engine